Clinico-demographic Profile of Chlorpyrifos-cypermethrin Combination Poisoning: A Retrospective Analysis at a Tertiary Care Hospital in East India.
DOI:
https://doi.org/10.48165/jfmt.2026.43.02.07Keywords:
Chlorpyrifos, Cypermethrin, combination poisoning, pesticide, clinical profile, demographic profile, epidemiology, public healthAbstract
Organophosphates are one of the most commonly encountered poisoning agents but their combination with pyrethroids is the least studied. The combination of chlorpyrifos 50% and cypermethrin 5% poisoning cases were studied to analyse the demographic profile and clinical features at presentation thereby forming the basis for treatment and the outcome. Material and Methods: It is a hospital based retrospective study of chlorpyrifos-cypermethrin combination poisoning cases which were brought to the Emergency Department of AIIMS, Bhubaneswar. Results: This study analysed 106 cases of chlorpyrifos-cypermethrin poisoning from April 2022–March 2024. Most cases (78.3%) involved combined poisoning, with 84.9% being intentional. Key symptoms included excessive salivation (p = 0.0005), lacrimation (p = 0.0140), respiratory crepitations (p = 0.0026) in mixed poisoning, head reeling in chlorpyrifos cases, and seizures in cypermethrin cases (p < 0.0001). The survival rate was 97.86%, with a 2.84% mortality rate. Conclusion: Chlorpyrifos-Cypermethrin poisoning causes severe cholinergic symptoms, requiring urgent care. Predominantly intentional among young males, it underscores the need for stricter regulations, better healthcare access, and mental health support.
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